Mono Sclerosis :: Stop MS in its tracks before it becomes Multiple

TYPES OF MS

Mono Sclerosis to be recognised by the medical profession (don't hold your breath).

One related area regarding MS pathogenesis is that of the outward manifestation of the disease. Most cases of MS start with a relapsing-remitting (RR) character which refers to short periods when new symptoms appear or old ones increase (attack or exacerbation) and long intervals when symptoms improve somewhat or stabilize (remissions).

On average it would appear a typical case involves about one attack a year (Sibley, 1992). Notably it has been found through MRI studies that lesion forming activity occurs even during remissions (Lai et al., 1996). Thus in many cases it would appear as if disease activity is essentially continuous with a waxing and waning character.

In many instances RRMS evolves into secondary progressive (or chronic progressive) MS where there are no clear relapses and remissions, only gradual deterioration.

In some cases, MS does not present in a relapsing-remitting manner but rather gradual deterioration begins at onset. This type of MS is known as primary progressive MS.